Linda Hamilton is well known as the star of Terminator (and T2), Beauty and the Beast, Dante's Peak and Point Last Seen. She was diagnosed at a young age with bipolar disorder, but resisted treatment until she was around 40 years old. In 1997 Linda Hamilton told interviewer Luaine Lee, "I'm on anti-depressants now. I will be on them for the rest of my life. It changed my world. There's depression, but also that extreme brilliant high. My manic spells are manageable and are great -- my work spaces where I'm doing so much. But what happens is then, all of a sudden, you plunge because you've depleted yourself on such a level that one day you wake up with a gigantic lump in your throat. And there it is. So I would fall down and just not be able to get myself up. Just the smallest thing would set me off."
A biographer notes that Linda's father, who died in an auto accident when she was five, was also diagnosed bipolar. What is not mentioned is whether her twin sister, Leslie, is manic depressive as well, which would be interesting to know.