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About Effexor -Venlafaxine

Speaking from Experience


Updated April 22, 2014

These are posts written by members of our About Bipolar Disorder Forum Community about the medication Effexor - generic Venlafaxine - an antidepressant chemically unrelated to any other currently on the market.

Please be aware that this material contains the personal experiences and opinions of consumers and in no way should be construed as medical advice.

Posts may have been edited by the Guides for spelling, grammar or clarity.

To read a discussion in its entirety, please follow the link preceding the quote.


    from Cason
    [Effexor] does have high potential to throw one into Mania but my pdoc says that if taken with a mood stablizer it is ok.

    from Pam
    I've taken Effexor for six years non-stop and had no escalation into a manic state. I have had bouts of rapid-cycling that may or may not've been related to the Effexor. They've been controlled by the addition of Depakote.

Med Combinations

    from Char
    I was once on Effexor and, like most of everybody else, I have to be on a stabilizer as well. I'm on Depakote three times a day.

    from Liverlegs
    Well all I can tell you is that they had me on Effexor XR only and it wasn't working. Then my doc tried Lithium as well as the Effexor. My depressions don't go as low as they used to and my manias aren't as high. I can almost say that I feel "normal." I haven't felt better about myself in a lot of years.

Poor Experiences

    from Char
    When I was on Effexor I did all right - not great and not bad. I felt like I could have been doing better though. But I was not on it long and I think my doctor could have upped the dose and I would have done great.

    from Makeower
    I began on Effexor about 3 1/2 years ago. It didn't balance my moods at all and didn't really help with my depression to a great deal.

    from Msonnier
    I have taken Celexa and Effexor XR. Neither has helped. I've been severely depressed for three months now.

    from Poolgoddess
    The Effexor has been a great help to me too but it's always worn off some after a dosage increase.

    more from Poolgoddess
    I tried Effexor XR, gradually upping it to the max, but it petered out.

    from Wonder
    I will always have a soft spot in my heart for Effexor, because that was the first antidepressant that worked for me. This was after almost a year of crippling, paralyzing depression. The doctor kept raising the dosage, while nothing happened. Finally, when the dose was high enough to give a buzz to an elephant, I started feeling better! The sad part is that the effects went away after a few months.

Positive Experiences

    from Cason
    I have been on Effexor for almost a year and after going through multiple AD's [antidepressants], it has been wonderful.

    from Jason
    Effexor, of all I've tried (Prozac.. Paxil.. etc.), is the only one that I could feel it in me. I mean feel it working. It was that period of time that I could actually be focused and do things.

    from Liverlegs
    I have been on Effexor for just over a year. I take it with Lithium. It took a few months but I have never felt better.

    from Pam
    With regard to Effexor's anti-depressant properties, I call it the "wonder drug"--it's worked for me when nothing else would.

Side Effects

    from Jenn
    The Effexor dissolves in my mouth right away and tastes absolutely horrible. Lately I'm getting a paranoid feeling about taking it -- I'm afraid that it will get stuck in my throat.

    from Likeayoyo
    I was on Celexa and I am now on Effexor. With the Celexa I felt no need for sex at all. With the Effexor it is a tad better.

    from Liverlegs
    I have been taking Effexor for just over a year. I take 150 mg in the am and 150 mg in the pm, along with Lithium. I noticed some dry mouth and also some trouble sleeping for the first while.

    from Msonnier
    I have been on Effexor now for a little over a month and it has not done anything I think but give me the shakes. I take Depakote and 150 mg of Effexor.

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