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Nortriptyline Side Effects

Bipolar Medications Library


Updated June 15, 2014

Here's a list of nortriptyline side effects. Nortriptyline is a tricyclic antidepressant sometimes sold under the brand names Pamelor and Aventyl (other brand names exist outside the US). This drug may be used in the treatment of bipolar disorder, other mood disorders such as depression, and also for some other conditions. People taking nortriptyline should be aware of the potential side effects of this drug.

Common Nortriptyline Side Effects:

Check with your doctor if any of the following side effects continue or are bothersome:

Dizziness; drowsiness; dry mouth; headache; increased appetite (may include craving for sweets); nausea; tiredness or weakness (mild); unpleasant taste; weight gain

Less Common Nortriptyline Side Effects:

Check with your doctor if any of the following side effects continue or are bothersome:

Diarrhea; heartburn; increased sweating; trouble sleeping (more common with the related medication protriptyline, especially when taken late in the day); vomiting

Always notify your doctor if you experience any of these nortriptyline side effects:

Less Common: Blurred vision; confusion or delirium; constipation (especially in the elderly); decreased sexual ability (more common with the related medications amoxapine and clomipramine); difficulty in speaking or swallowing; eye pain; fainting; fast or irregular heartbeat (pounding, racing, skipping); hallucinations; loss of balance control; mask-like face; nervousness or restlessness; problems in urinating; shakiness or trembling; shuffling walk; slowed movements; stiffness of arms and legs

Rare: Anxiety; breast enlargement in both males and females; hair loss; inappropriate secretion of milk in females; increased sensitivity to sunlight; irritability; muscle twitching; red or brownish spots on skin; ringing, buzzing, or other unexplained sounds in the ears; seizures (more common with clomipramine); skin rash and itching; sore throat and fever; swelling of face and tongue; swelling of testicles (more common with the related medication amoxapine); trouble with teeth or gums (more common with the related medication clomipramine); weakness; yellow eyes or skin

Nortriptyline Withdrawal Side Effects - Notify your doctor:

Headache; irritability; nausea, vomiting, or diarrhea; restlessness; trouble in sleeping, with vivid dreams; unusual excitement

Nortriptyline Overdose Effects - Notify doctor or go to emergency room immediately:

Confusion; convulsions (seizures); disturbed concentration; drowsiness (severe); enlarged pupils; fast, slow, or irregular heartbeat; fever; hallucinations (seeing, hearing, or feeling things that are not there); restlessness and agitation; shortness of breath or troubled breathing; unusual tiredness or weakness (severe); vomiting

Other nortriptyline side effects not listed above may also occur in some patients. If you notice any other side effects, check with your doctor.

Disclaimer: This is not intended to be all-inclusive or to replace information provided by your doctor or with the prescription from the manufacturer.

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