Trazodone Side EffectsCheck with your doctor if any of the following side effects continue or are bothersome:
More Common: Dizziness or lightheadedness; drowsiness/sleepiness; dry mouth; headache; nausea; fatigue; blurred vision; constipation; diarrhea; back pain; sexual dysfunction (decreased desire or performance ability)
Note: Because trazodone's sedating effect is so common that the drug is prescribed for sleep problems, it is important not to engage in hazardous activities, including driving, until you know how this drug affects you.
Always notify your doctor as soon as possible if you experience any of these side effects:Less Common: Abdominal pain; muscle aches; problems with coordination or memory; migraine; tingling; agitation; disorientation; shortness of breath; night sweats; urgent need to urinate; swelling; vomiting; unpleasant taste; visual disturbance; confusion; drop in blood pressure when standing up (orthostatic hypotension); muscle tremors
Rare: Hearing problems; tinnitus; dry eye; abnormal gait; muscle twitching; amnesia; sensitivity to light; acne; eye pain; acid reflux; speech problems; bladder pain or incontinence; flushing (skin becoming red and warm); fainting (syncope); fast or slow heartbeat; skin rash; unusual excitement
Stop taking this medicine and seek emergency medical attention if the following side effect occurs:Rare: Painful, prolonged erection of the penis. This condition, called priapism, can result in permanent damage to erectile tissues if not treated promptly.
Overdose Effects - Notify Doctor Immediately:Drowsiness; loss of muscle coordination; nausea and vomiting; priapism (see above). Rarely, respiratory arrest, seizures and heart problems have been reported.
Trazodone Withdrawal Symptoms:Anxiety; agitation; sleep disturbances. Gradual discontinuation of trazodone is recommended to minimize these symptoms.
Trazodone Black Box WarningLike all antidepressants, the prescribing information for trazodone is required to carry a warning regarding the increased possibility of suicidal thinking or behavior in young adults (24 and under), adolescents and children. See Antidepressant Medications - Box Warning for the full text of this warning.
Other possible rare but serious side effects:
- Serotonin Syndrome
- Neuroleptic Malignant Syndrome
- Abnormal bleeding, especially when combined with drugs that can irritate the stomach, including aspirin, ibuprofen and naproxen
Source: Drugs@FDA. Oleptro Approved Label. 5 May 2011.