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Amoxapine / Asendin Side Effects
Bipolar Medications Library

By Kimberly Read & Marcia Purse, About.com

Updated July 15, 2006

About.com Health's Disease and Condition content is reviewed by the Medical Review Board

Asendin - generic Amoxapine - is a tricyclic antidepressant that may be used in treating bipolar disorder.

Common Asendin Side Effects:

Check with your doctor if any of the following side effects continue or are bothersome:

Dizziness; drowsiness; dryness of mouth; headache; increased appetite (may include craving for sweets); nausea; tiredness or weakness (mild); unpleasant taste; weight gain

Less Common Asendin Side Effects:

Check with your doctor if any of the following side effects continue or are bothersome:

Diarrhea; heartburn; increased sweating; trouble in sleeping (more common with protriptyline, especially when taken late in the day); vomiting

SPECIAL WARNING: Stop taking Asendin / Amlodipine and get emergency help immediately if any of the following side effects occur:

Rare:

Convulsions (seizures); difficult or fast breathing; fever with increased sweating; high or low (irregular) blood pressure; loss of bladder control; muscle stiffness (severe); pale skin; unusual tiredness or weakness

Notify Doctor As Soon As Possible:

Less Common: Blurred vision; confusion or delirium; constipation (especially in the elderly); decreased sexual ability (more common with amoxapine and clomipramine); difficulty in speaking or swallowing; eye pain; fainting; fast or irregular heartbeat (pounding, racing, skipping); hallucinations; loss of balance control; mask-like face; nervousness or restlessness; problems in urinating; shakiness or trembling; shuffling walk; slowed movements; stiffness of arms and legs; lip smacking or puckering; puffing of cheeks; rapid or worm-like movements of tongue; uncontrolled chewing movements; uncontrolled movements of hands, arms, or legs

Rare: Anxiety; breast enlargement in both males and females; hair loss; inappropriate secretion of milk - in females; increased sensitivity to sunlight; irritability; muscle twitching; red or brownish spots on skin; ringing, buzzing, or other unexplained sounds in the ears; seizures (more common with clomipramine); skin rash and itching; sore throat and fever; swelling of face and tongue; swelling of testicles (more common with amoxapine); trouble with teeth or gums (more common with clomipramine); weakness; yellow eyes or skin

Asendin Withdrawal Side Effects - Notify Doctor:

Headache; irritability; nausea, vomiting, or diarrhea; restlessness; trouble in sleeping, with vivid dreams; unusual excitement; lip smacking or puckering; puffing of cheeks; rapid or worm-like movements of the tongue; uncontrolled chewing movements; uncontrolled movements of arms or legs

Asendin Overdose Effects - Notify Doctor:

Confusion; convulsions (seizures); disturbed concentration; drowsiness (severe); enlarged pupils; fast, slow, or irregular heartbeat; fever; hallucinations (seeing, hearing, or feeling things that are not there); restlessness and agitation; shortness of breath or troubled breathing; unusual tiredness or weakness (severe); vomiting

Other Asendin side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

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