In medical terms, lethargy can mean a state of sluggish inactivity with a lack of interest in doing anything. It can also mean abnormal drowsiness or a state of mental numbness, or both. A person in one of these states can be described as "lethargic."
Jane was diagnosed with clinical depression when she became so lethargic that she just sat in her chair all day not wanting to do anything that would get her up and moving.

