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Street Drugs and Bipolar Disorder: Ecstasy

By Kimberly Read & Marcia Purse, About.com

Updated November 04, 2007

About.com Health's Disease and Condition content is reviewed by the Medical Review Board

by Kimberly Read

Name: Ecstasy

Chemical: Methylenedioxymethamphetamine (MDMA)

AKA: E, X, M, XTC, clarity, essence, Adam, beans, rolls, decadence, M & M

Classification: Psychedelic Amphetamine

Forms: Most commonly found as tablets which are ingested; may also be seen as a powder which is in ingested and may be snorted or smoked (rare); very rarely it may be injected (NIDA).

Addiction Potential: Ecstasy is not known to be physically addictive (DanceSafe). However, it does have the potential to be psychology addictive, becoming quite an obsession for some people. There is also the potential for tolerance to build (Erowid).

Effects: MDMA is a "synthetic psychoactive drug" that combines both "mildly hallucinogenic and amphetamine-like effects" (ONDCP). The more common physical effects of MDMA include an increase in energy, heightened awareness of the senses, visual distortions, appetite loss, nystagmus (rapid, involuntary eye jiggling), restlessness, change in body temperature regulation, jaw clenching and teeth grinding (Erowid). While the overall experience can vary widely from person to person, psychologically MDMA is a drug that increases empathy. These effects include an extreme mood lift, increased communication, a sense of closeness and belonging as well as a strong desire to be hugged and touched by people (Erowid).

Drug Interactions: Do NOT mix Ecstasy with Monoamine Oxidase Inhibitors (MAOI). The MAOIs, such as Parnate and Nardil among many others, are prescribed for depression. Deaths have occurred due to interactions between Ecstasy and the MAO Inhibitors (DanceSafe).

Complications with Bipolar Disorder: Some users, most especially those who frequently take Ecstasy or take high doses, experience depression when coming back down. Those already struggling with depression (unipolar or bipolar) may find that Ecstasy exacerbates the condition (DanceSafe).

Works Cited

DanceSafe. (Accessed: 2000, September 10). What Is Ecstasy?

Erowid. (2000, August 21). MDMA Basics.

National Institute on Drug Abuse (NIDA). (1999, November). NIDA InfoFacts: MDMA (Ecstasy).

Office of National Drug Control Policy (ONDCP). (Accessed: 2000, September 11). Information About "Club" Drug Use.

For Further Study

Self- Medicating: When the Cure IS the Disease
Additional Ecstasy Links

Explore Bipolar Disorder
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