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Cymbalta Side Effects (Duloxetine)

Bipolar Medications Library

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Updated May 15, 2014

Cymbalta (duloxetine) is an antidepressant medication that is also used to treat diabetic neuropathy. It is classed as an SNRI - Serotonin-Norepinephrine Reuptake Inhibitor. It is used to treat depressive symptoms including the aches and pains that can be caused by depression.

Common Cymbalta Side Effects:

Check with your doctor if any of the following side effects continue or are bothersome:

Cough; nausea; diarrhea; constipation; dizziness; dry mouth; fever; frequent urination; headache; lack or loss of strength; loss of appetite; muscle aches; sleepiness or unusual drowsiness; sleeplessness; sore throat; stuffy or runny nose; increased sweating; difficulty sleeping; insomnia; unusual tiredness or weakness; vomiting; weight loss

Less Common Cymbalta Side Effects:

Check with your doctor if any of the following side effects continue or are bothersome:

Abnormal orgasm; acid or sour stomach; belching; change or problem with ejaculation; decreased interest in sex; difficulty in moving; erectile dysfunction; fear; feeling of warmth or redness of the face, neck, arms and occasionally, upper chest; heartburn; indigestion; joint pain; muscle aching or cramping; muscle pains or stiffness; nervousness; shakiness in legs, arms, hands, feet; stomach discomfort upset or pain; sudden sweating; swollen joints; trembling or shaking of hands or feet

Always notify your doctor if you experience these Cymbalta side effects:

Abdominal or stomach pain; fast heartbeat; blistering, peeling, loosening of skin; chills; clay-colored stools; cold sweats; confusion; convulsions; dark urine; decreased urine output; difficulty swallowing; eye pain; general tiredness; itching, puffiness, or swelling of the eyelids or around the eyes, face, lips or tongue; increase thirst; itching; joint or muscle pain; swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, and/or sex organs; light-colored stools; red irritated eyes; red skin lesions, often with a purple center; redness of skin; sores, ulcers, or white spots in mouth or on lips; swelling of face, ankles, or hands; tearing; tightness in chest; bad breath; upper right abdominal pain; wheezing; yellow eyes and skin

If you experience any of the following serious Cymbalta side effects, stop taking Cymbalta and contact your doctor immediately or seek emergency medical treatment:

Difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; hives; an irregular heartbeat or pulse; low blood pressure; dizziness, fainting, lightheadedness or weakness; high blood pressure; severe headache; blurred vision or other difficulty seeing; chills or fever; unusual bleeding or bruising; rash; coma; vomiting of blood

Other Cymbalta side effects not listed above may also occur in some patients. If you notice anything unusual while taking Cymbalta, check with your doctor.

More on Cymbalta and Other Bipolar Medications:

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