Agranulocytosis

Definition:
Agranulocytosis means low white blood cell count. Without enough white blood cells, your body may not be able to fight infection. Since this side effect can be dangerous, be sure to report high fevers and painful sore throats to your doctor as soon as possible.

Anti-thyroid medications have a relatively high incidence of causing this condition. Some psychiatric drugs that can cause agranulocytosis include, but are not limited to:

• Clozaril / clozapine (see Clozaril Black Box Warnings
• Tegretol / carbamazepine
• Depakote / divalproex sodium
• Remeron / mirtazapine
• Zyprexa / olanzapine

Reference: Zyprexa.com (2006). Recognizing Side Effects That Require Immediate Attention. 9/7/06. (no longer online)

Pronunciation:
ay-GRAN-yoo-loh-cy-TOH-sis

Also Known As:
Granulocytopenia; Granulopenia; Neutropenia (slightly different meaning, but often used interchangeably)